Star Manly playmaker Daly Cherry-Evans is in doubt with an ankle injury this week.
All the player rumours and team changes heading into Round 7 of the NRL Telstra Premiership season.
Rabbitohs v Bulldogs
Rabbitohs: Souths are 1-17, with Joel Reddy and Alex Johnston dropping off an extended bench. Ben Te'o and George Burgess are both out suspended.
Bulldogs: Giant prop Sam Kasiano will come on to the bench for his first NRL game this season at the expense of Pat O'Hanlon. The Bulldogs this week lost Frank Pritchard to a long-term pectoral injury. Moses Mbye will drop off the extended bench.
Knights v Broncos
Knights: Kade Snowden will miss the match following last week's concussion, with Adam Cuthbertson set to replace him in the 17. Jake Mamo will make his NRL debut on the wing in place of the injured Akuila Uate, despite Josh Mantellato being named in the side earlier in the week. Zane Tetevano will start, with Willie Mason dropping to the bench.
Broncos: Sam Thaiday is out with a calf injury, meaning Marty Kennedy will start in the front row and Corey Parker pushed to lock. Jake Granville will play his first NRL game of the year off the bench. Todd Lowrie drops out.
Sea Eagles v Cowboys
Sea Eagles: Daly Cherry-Evans is out with an ankle injury - Kieran Foran moves to halfback and Jamie Lyon to five-eighth, while Peta Hiku shifts into the centres and David Williams comes on to the wing. Jason King drops off the bench.
Cowboys: Kane Linnett is out with a back injury, bringing Kyle Feldt into the centres. Curtis Rona will make his debut on the wing in place of the injured Antonio Winterstein.
Dragons v Warriors
Dragons: Dylan Farrell is out with a pectoral injury, with Joel Thompson likely to switch to the centres this week – although he faces a cognitive test himself after last week's concussion. Kyle Stanley, Charly Runciman and Nathan Green are other options to replace Farrell in the side.
Warriors: No changes expected, with Konrad Hurrell dropped to the NSW Cup and Jayson Bukuya and Ben Henry returning from injury.
Sharks v Roosters
Sharks: Anthony Tupou could be a late inclusion for his first game of the season if he passes a fitness test on Friday. Luke Lewis is a week or two away from returning to the side, while captain Paul Gallen is getting close to fitness.
Roosters: No changes expected.
Raiders v Storm
Raiders: There could be late changes at Canberra with Ricky Stuart suggesting he has several players in doubt.
Storm: Mahe Fonua is set to replace Will Chambers, who will miss two weeks with a shoulder charge suspension.
Eels v Wests Tigers
Eels: Ben Smith is battling to return from a finger injury, and Darcy Lussick returns after a four-week suspension.
Tigers: Joel Luani will get his first run in the Wests Tigers No.9 for the year as the Tigers begin a stretch of games without injured skipper Robbie Farah. Liam Fulton is in some doubt with a shoulder injury while Kurtis Rowe will play despite picking up a cork last week.
Panthers v Titans
Panthers: David Simmons could make his return from a hamstring injury on Monday, which would bump rookie Dallin Watene-Zelezniak out of the side.
Titans: Anthony Don is in doubt with a finger injury, while William Zillman is out of the squad after failing to recover from his hamstring injury. The Titans have confirmed Kalifa Faifai Loa will travel with the squad as 18th man.